General Toxicology

Introductory course on basic principles in toxicology, organ-specific toxic effects and risk assessment.

After successful completion of this course students are expected to be able to:

• summarize important generalized toxicological (biochemical) mechanisms underlying toxic responses following exposure to toxic chemicals;
• interpret the consequences of physiological processes on toxic responses in the human body;
• apply some important mechanisms (modes of action) of toxic chemicals that underlie the adverse effects observed to important toxic chemicals in food and the environment;
• Argue how non-laboratory animal data can be used in the toxicological risk assessment of chemicals;
• recall what type of data is required by regulatory bodies for the safety assessment of chemicals;
• design and execute a comprehensive toxicological concentration-response experiment and critically report and discus the results;
• apply the basic principles of risk assessment of chemicals in food and the environment.

Mandatory Knowledge:
ZSS06100 Laboratory Safety

https://wur.osiris-student.nl/onderwijscatalogus/extern/cursus?cursusid=817245&taal=en