Cell mechanobiology and engineering

• Introduction to mechanobiology
• Mechanosensing and mechanotransduction
• Cell and matrix mechanics
• Cellular and mammalian gene engineering approaches
• Biophysical manipulation
• Measurement techniques
• Reconstructing cell–matrix interactions

For Student Mobility Alliance students: The course will be delivered fully on campus. The final exam is a written on campus exam.

Upon completion of the course, the student can:

1. Explain the scientific concept and the multidisciplinary scope of mechanobiology, as well as its importance in human physiology and diseases.
2. Specify the essential players in the interactions between the cell and its environment and understands their primary roles.
3. Describe the mechanical response of cells and extracellular matrices and its structural underlying.
4. Describe the various state-of-the-art engineering approaches to dissect the principles behind cell–matrix and cell-cell interactions.
5. Independently identify and propose how dynamic cell–matrix and cell-cell interactions can be harnessed for rational design of biomaterials and to manipulate cell behavior in regenerative medicine applications.

You must meet the following requirements

• Completed Final examination Bsc program

• Introduction to Cell Mechanics and Mechanobiology, by Jacobs, Huang, Kwon.
• Lecture handouts
• Articles and possible other materials communicated before/during the course