Clinical chemistry

First the principles of medical decision making with concepts as test specificity and sensitivity and predictive value of laboratory data in relation to prevalence of the disease are reviewed. The influence of fysiology and pathofysiology on the concentration of specific analytes in body fluids and methods to analyse these components in modern clinical laboratories are considered. Case histories will be used to illustrate and discuss concepts and applications of clinical chemistry in the diagnostic process. Optional is to visit the clinical laboratory of Catharina Ziekenhuis.
To succeed for the exam the lectures’ content needs to be studied thoroughly on a weekly basis. The facts and the understanding of the facts are tested in the final exam.

This course illustrates the application of laboratory medicine in clinical diagnostics.

You must meet the following requirements

• Completed Final examination Bsc program

• William J Marshall, Clinical Chemistry 9th edition (2021), Mosby Elsevier, ISBN-13: 978-0-702-0-7936-8, 50 euro (strongly recommended
• information and hand-outs with power-point presentations